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| | | | World History timeline |
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| 1463 |
| | | The Chimu empire in Peru is conquered by the Incas under the leadership of Pachacuti's son Topa | |
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| 1464 |
| | | After his death in 1464, Cosimo de' Medici acquires the posthumous title pater patriae – father of the fatherland | |
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| 1464 |
| | | Mehmed II and the Ottoman Turks conquer Bosnia, where a large number of noble families convert to Islam | |
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| c. 1465 |
| | | The Sicilian artist Antonello da Messina adopts the Flemish technique of painting in oils | |
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| 1466 |
| | | In the treaty of Torun the Teutonic knights finally cede Prussia to Poland | |
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| 1466 |
| | | The Portuguese settlers on the Cape Verde islands are granted a monopoly on the new slave trade | |
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| 1468 |
| | | Skanderbeg dies and Albania becomes fully absorbed into the Ottoman empire | |
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| c. 1468 |
| | | Jerome van Aken works almost exclusively in his native s' Hertogenbosch, from which he derives the name Hieronymus Bosch | |
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| 1469 |
| | | Thomas Malory, in gaol somewhere in England, compiles Morte d'Arthur – an English account of the French tales of King Arthur | |
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| 1469 |
| | | The Orkneys and Shetlands come into the possession of James III of Scotland with the dowry of Margaret of Denmark | |
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| 1469 |
| | | The marriage of Ferdinand and Isabella unites the crowns of Aragon and Castile, creating virtually a unified Spain | |
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| 1470 |
| | | The first Italian printing press is set up in Venice, which soon rivals Germany for the quality of its printing | |
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| c. 1470 |
| | | Sandro Botticelli is established as one of the leading painters of Florence, working in particular for the Medici | |
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| 1471 |
| | | The new pope, Sixtus IV, secures his name in history, establishing the Sistine chapel and the Sistine choir | |
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| 1471 |
| | | Topa succeeds his father, Pachacuti, as emperor of the Incas | |
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| 1472 |
| | | Leonardo da Vinci joins the painters' guild in Florence, probably after training with Verrocchio | |
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| c. 1475 |
| | | Tommaso Portinari, the Medici agent in Bruges, commissions an altarpiece from Hugo van der Goes for his family church in Florence | |
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| c. 1475 |
| | | With Constantinople in Turkish hands, Moscow begins to see itself as the centre of Orthodox Christianity - or the third Rome | |
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| 1475 |
| | | Edward IV, landing at Calais with a large army, is bought off at Picquigny with a bribe - ending his attempt to revive the Hundred Years' War | |
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| c. 1475 |
| | | Giovanni Bellini becomes the key figure in the development of the Renaissance style in Venice | |
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| 1476 |
| | | The Swiss win a decisive victory at Morat over the army of Charles the Bold, duke of Burgundy | |
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| c. 1476 |
| | | Caxton establishes the first English printing press in London, after working in the new trade in Bruges | |
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| 1477 |
| | | Ptolemy's concept of the world, with the Atlantic stretching to China and India, is printed in Bologna – fifteen years before Columbus sails west | |
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| 1477 |
| | | Maximilian, heir to Austria, weds Mary, heiress to Burgundy, in the first of the great marriage alliances which form the Habsburg empire | |
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| 1478 |
| | | A plot by the Pazzi family, with papal connivance, results in the murder of Guiliano de' Medici during high mass in Florence's cathedral | |
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| 1478 |
| | | Ivan III subdues proudly independent Novgorod, removing the city's famous bell | |
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| c. 1480 |
| | | Leonardo da Vinci takes a professional interest in the new science of fortification | |
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| c. 1480 |
| | | The name of Constantinople changes to Istanbul, a word based on the everyday Greek name for the city | |
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| c. 1480 |
| | | The Maravi Confederacy is formed by Bantu tribes and soon wins control over a large region between Lake Nyasa and the Zambezi | |
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| c. 1480 |
| | | An increase in trade through the central Sahara benefits the Songhay, with their capital at Gao, at the expense of Mali | |
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| c. 1480 |
| | | Botticelli paints the Birth of Venus and Spring for the villa of a Medici cousin of Lorenzo the Magnificent | |
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| 1480 |
| | | Ivan III, grand prince of Russia, becomes the first to deny the Mongols of the Golden Horde their annual tribute of tax | |
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| 1480 |
| | | Tomas de Torquemada, from a family of converted Jews, is appointed Spain's first Grand Inquisitor | |
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| 1481 |
| | | Civil war between squabbling Swiss cantons is averted by the diplomcy of a hermit, Brother Klaus, at the Convention of Stans | |
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| 1483 |
| | | The English king Edward IV dies and his succeeded by his 12-year-old son as Edward V | |
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